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eBook details

• Title: Inhibition of C[Cl.Sub.4]-Induced Liver Fibrosis by Piper Longum Linn.?(Short COMMUNICATION)
• Author : Phytomedicine: International Journal of Phytotherapy & Phytopharmacology
• Release Date : January 01, 2006
• Genre: Life Sciences,Books,Science & Nature,
• Pages : * pages
• Size : 194 KB

Description

Abstract This study was carried out to evaluate the antifibrotic effect of ethanol extract of the fruits of Indian herb Piper longum Linn. Liver fibrosis was induced in rats by C[Cl.sub.4] administration. The extent of liver fibrosis was assessed, by measuring the level of liver hydroxy proline (HP) and serum enzyme levels. Following C[Cl.sub.4] administration HP was significantly increased and serum enzyme levels were elevated. Treatment with the ethanol extract of Piper longum Linn. reduced the HP and also the serum enzymes. The liver weight that increased following C[Cl.sub.4] administration due to the deposition of collagen was reduced by the ethanol extract. Hence, it is concluded that this extract inhibits liver fibrosis induced by C[Cl.sub.4].

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